Glucose Transporter 8 Blocking Peptide peptide (STJ504148)

SKU:
STJ504148-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Glucose Transporter 8 Blocking Peptide is synthetically produced from the 400-500 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: SLC2A8
Gene ID: 29988
Uniprot ID: SL2A8_HUMAN
Immunogen Region: 400-500
Immunogen: Synthetic peptide taken within amino acid region 400-500 on GLUT8 protein.
Tissue Specificity Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Function Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate.
Peptide Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8
Glucose Transporter Type 8
Glut-8
Glucose Transporter Type X1
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Principally Intracellular
May Move Between Intracellular Vesicles And The Plasma Membrane
The Dileucine Internalization Motif Is Critical For Intracellular Sequestration
Alternative Peptide Names Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 protein
Glucose Transporter Type 8 protein
Glut-8 protein
Glucose Transporter Type X1 protein
SLC2A8 protein
GLUT8 protein
GLUTX1 protein

Information sourced from Uniprot.org

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