FOLR2 Blocking Peptide for STJ501074 peptide (STJ505522)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1-50 on rat Folate receptor 2 protein.
General Information
| Short Description | FOLR2 Blocking Peptide for STJ501074 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on rat Folate receptor 2 protein. |
| Immunogen Region | 1-50 |
| Specificity | This blocking peptide is recommended for use in combination with FOLR2 antibody, STJ501074 |
Additional Info
| Background | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
Information sourced from Uniprot.org