Ferritin Blocking Peptide peptide (STJ505569)
SPECIFICATIONS
ImmunogenFull length Ferritin Protein.
General Information
| Short Description | Ferritin Blocking Peptide is synthetically produced from the Full Length sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:2, 500-1:5, 000IHC: 1:50-1:150ICC: 1:50-1:150 |
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | FTH1 |
| Gene ID | 2495 |
| Uniprot ID | FRIH_HUMAN |
| Immunogen | Full length Ferritin Protein. |
| Immunogen Region | Full Length |
Additional Info
| Tissue Specificity | Expressed in the liver. |
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron. |
| Peptide Name | Ferritin Heavy ChainFerritin H SubunitCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed |
| Database Links | Reactome: R-HSA-3000480Reactome: R-HSA-432722Reactome: R-HSA-6798695Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmLysosomeCytoplasmic VesicleAutophagosome |
| Alternative Peptide Names | Ferritin Heavy Chain proteinFerritin H Subunit proteinCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed proteinFTH1 proteinFTH proteinFTHL6 proteinOK proteinSW-cl.84 proteinPIG15 protein |
Information sourced from Uniprot.org