Fbx32 Positive Control for STJ500183 peptide (STJ503705)
SPECIFICATIONS
General Information
| Short Description | Fbx32 Positive Control for STJ500183 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | FBXO32 |
| Gene ID | 114907 |
| Uniprot ID | FBX32_HUMAN |
| Specificity | This is positive control is recommended for use in combination with Fbx32 antibody STJ500183. |
Additional Info
| Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
| Peptide Name | F-Box Only Protein 32Atrogin-1Muscle Atrophy F-Box ProteinMafbx |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-9615017Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmNucleusShuttles Between Cytoplasm And The Nucleus |
| Alternative Peptide Names | F-Box Only Protein 32 proteinAtrogin-1 proteinMuscle Atrophy F-Box Protein proteinMafbx proteinFBXO32 protein |
Information sourced from Uniprot.org