Fbx32 Blocking Peptide for STJ500183 peptide (STJ503688)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 240-280 on Atr1 protein.
General Information
| Short Description | Fbx32 Blocking Peptide for STJ500183 is synthetically produced from the 240-280 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | FBXO32 |
| Gene ID | 114907 |
| Uniprot ID | FBX32_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 240-280 on Atr1 protein. |
| Immunogen Region | 240-280 |
| Specificity | This blocking peptide is recommended for use in combination with Fbx32 antibody, STJ500183 |
Additional Info
| Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
| Peptide Name | F-Box Only Protein 32Atrogin-1Muscle Atrophy F-Box ProteinMafbx |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-9615017Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmNucleusShuttles Between Cytoplasm And The Nucleus |
| Alternative Peptide Names | F-Box Only Protein 32 proteinAtrogin-1 proteinMuscle Atrophy F-Box Protein proteinMafbx proteinFBXO32 protein |
Information sourced from Uniprot.org