Dystrophin Positive Control for STJ507808 peptide (STJ507811)
SPECIFICATIONS
ImmunogenPartially purified rat aquaporin 7 protein.
General Information
| Short Description | Dystrophin Positive Control for STJ507808 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | DMD |
| Gene ID | 1756 |
| Uniprot ID | DMD_HUMAN |
| Immunogen | Partially purified rat aquaporin 7 protein. |
| Specificity | This is positive control is recommended for use in combination with Dystrophin antibody STJ507808. |
Additional Info
| Function | Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. |
| Peptide Name | Dystrophin |
| Database Links | Reactome: R-HSA-3000171Reactome: R-HSA-390522 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPostsynaptic Cell MembraneIn Muscle CellsSarcolemma Localization Requires The Presence Of Ank2While Localization To Costameres Requires The Presence Of Ank3Localizes To Neuromuscular Junctions (Nmjs)In Adult MuscleNmj Localization Depends Upon Ank2 PresenceBut Not In Newborn Animals |
| Alternative Peptide Names | Dystrophin proteinDMD protein |
Information sourced from Uniprot.org