Dopamine D2 Receptor Blocking Peptide peptide (STJ503942)

SKU:
STJ503942-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Dopamine D2 Receptor Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: DRD2
Gene ID: 1813
Uniprot ID: DRD2_HUMAN
Immunogen: Synthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein.
Tissue Specificity Isoform 1: Expressed in the anterior pituitary gland. Isoform 2: Expressed in the anterior pituitary gland.
Post Translational Modifications Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Peptide Name D(2 Dopamine Receptor
Dopamine D2 Receptor
Database Links Reactome: R-HSA-390651
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Peptide Names D(2 Dopamine Receptor protein
Dopamine D2 Receptor protein
DRD2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance