Dopamine beta hydroxylase Positive Control for STJ507829 peptide (STJ507834)

SPECIFICATIONS
HostRabbit
ImmunogenSynthetic peptide taken within amino acid region 125-178 on mouse Dopamine beta hydroxylase.
STJ507834-5
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General Information

Short DescriptionDopamine beta hydroxylase Positive Control for STJ507829 is synthetically produced from the 125-178 sequence and is suitable for use in western blot applications.
ApplicationsWB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

FormulationProvided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolDbh
Gene ID13166
Uniprot IDDOPO_MOUSE
ImmunogenSynthetic peptide taken within amino acid region 125-178 on mouse Dopamine beta hydroxylase.
Immunogen Region125-178
SpecificityThis is positive control is recommended for use in combination with Dopamine beta hydroxylase antibody STJ507829.

Additional Info

Post Translational Modifications Proteolytic cleavage after the membrane-anchor leads to the release of the soluble form. N-glycosylated.
Function Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters.
Peptide Name Dopamine Beta-Hydroxylase
Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase
Database Links Reactome: R-MMU-209905
Cellular Localisation Soluble Dopamine Beta-Hydroxylase: Cytoplasmic Vesicle
Secretory Vesicle Lumen
Cytoplasmic Vesicle
Secretory Vesicle
Chromaffin Granule Lumen
Secretory Vesicle Membrane
Single-Pass Type Ii Membrane Protein
Chromaffin Granule Membrane
Alternative Peptide Names Dopamine Beta-Hydroxylase protein
Dopamine Beta-Monooxygenase Cleaved Into - Soluble Dopamine Beta-Hydroxylase protein
Dbh protein

Information sourced from Uniprot.org

Citations

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