DOC2B Blocking Peptide for STJ500786 peptide (STJ503960)
SPECIFICATIONS
ImmunogenSynthetic Peptide taken within amino acid region 360-412 on DOC2b gene.
General Information
| Short Description | DOC2B Blocking Peptide for STJ500786 is synthetically produced from the 360-412 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Doc2b |
| Gene ID | 81820 |
| Uniprot ID | DOC2B_RAT |
| Immunogen | Synthetic Peptide taken within amino acid region 360-412 on DOC2b gene. |
| Immunogen Region | 360-412 |
| Specificity | This blocking peptide is recommended for use in combination with DOC2B antibody, STJ500786 |
Additional Info
| Tissue Specificity | Expressed in brain.highly enriched in neurons. |
| Function | Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes. |
| Peptide Name | Double C2-Like Domain-Containing Protein BetaDoc2-Beta |
| Cellular Localisation | CytoplasmCytoplasmic GranuleCell MembranePeripheral Membrane ProteinTranslocates To The Plasma Membrane In A Calcium-Dependent Manner |
| Alternative Peptide Names | Double C2-Like Domain-Containing Protein Beta proteinDoc2-Beta proteinDoc2b protein |
Information sourced from Uniprot.org