Cynomolgus SIRP-alpha/CD172a protein (Recombinant) (C-His) (STJP020272)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Cynomolgus SIRP-alpha/CD172a Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Glu31-Arg370) of Cynomolgus CD172a fused with His tag at the C-terminus.
General Information
| Short Description | Recombinant-Cynomolgus SIRP-alpha/CD172a-C-His protein was developed in hek293 cells using the region Glu31-Arg370. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Cynomolgus SIRP-alpha/CD172a Protein is produced by Expi293 expression system. The target protein is expressed with sequence ( Glu31-Arg370) of Cynomolgus CD172a fused with His tag at the C-terminus. |
| Immunogen Region | Glu31-Arg370 |
Additional Info
| Background | Signal regulatory protein Alpha (SIRP Alpha ) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRP Alpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "donβ²t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP Alpha and inhibit macrophage-mediated destruction. |
Information sourced from Uniprot.org