Cynomolgus CD3E&CD3G protein (Recombinant) (C-hFc) (STJP020113)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human BCMA/TNFRSF17 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Asp20-Arg687 (Q95LI52) & Gln23-Thr113 (Q95LI7) ) of cynomolgus CD3E&CD3G (Accession #Q95LI5.2 & Q95LI7) fused with an F
General Information
| Short Description | Recombinant-Cynomolgus CD3E&CD3G-C-hFc protein was developed in hek293 cells using the region Asp20-Arg687. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.2 Mu m filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Immunogen | Recombinant Human BCMA/TNFRSF17 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Asp20-Arg687 (Q95LI52) & Gln23-Thr113 (Q95LI7) ) of cynomolgus CD3E&CD3G (Accession #Q95LI5.2 & Q95LI7) fused with an F |
| Immunogen Region | Asp20-Arg687 |
| Immunogen Sequence | QDGNEEMGSITQTPYQVSIS GTTVILTCSQHLGSEAQWQH NGKNKEDSGDRLFLPEFSEM EQSGYYVCYPRGSNPEDASH HLYLKARVCENCMEMDQSFE ENRKLNVYNQEDGSVLLTCH VKNTNITWFKEGKMIDILTA HKNKWNLGSNTKDPRGVYQC KGSKDKSKTLQVYYRMCQNC IELNAAT |
Additional Info
| Background | T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR) , TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. |
Information sourced from Uniprot.org