| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Immunogen Region: | Trp27-Cys554 |
| Immunogen: | Recombinant Cynomolgu 5 NA-Nucleotidase/NT5E/CD73 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Trp27-Cys554) of Cynomolgus 5 NA-Nucleotidase/NT5E/CD73 fused with His tag at the C-terminus. |
| Background | CD73, also known as ecto-5 NA-nucleotidase, is an enzyme that in humans is encoded by the NT5E gene.CD73 commonly serves to convert AMP to adenosine.The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. A? deficiency of CD73 occurs in a variety of immunodeficiency diseases. |
Information sourced from Uniprot.org
