CXCR2 Blocking Peptide for STJ506205 peptide (STJ505897)

Name: CXCR2 Blocking Peptide for STJ506205 peptide (STJ505897)
SKU: STJ505897-250
Price: 260.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ImmunogenSynthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2.

STJ505897-250

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Short Description	CXCR2 Blocking Peptide for STJ506205 is synthetically produced from the 445-538 sequence and is suitable for use in western blot applications.
Applications	Immunodepletion/Immunocompetition
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	Cxcr2
Gene ID	12765
Uniprot ID	CXCR2_MOUSE
Immunogen	Synthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2.
Immunogen Region	445-538
Specificity	This blocking peptide is recommended for use in combination with CXCR2 antibody, STJ506205

Post Translational Modifications	Phosphorylated upon ligand binding.which is required for desensitization.
Function	Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Peptide Name	C-X-C Chemokine Receptor Type 2 Cxc-R2 Cxcr-2 Gro/Mgsa Receptor High Affinity Interleukin-8 Receptor B Il-8r B Cd Antigen Cd182
Database Links	Reactome: R-MMU-380108 Reactome: -MMU-418594 Reactome: -MMU-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Peptide Names	C-X-C Chemokine Receptor Type 2 protein Cxc-R2 protein Cxcr-2 protein Gro/Mgsa Receptor protein High Affinity Interleukin-8 Receptor B protein Il-8r B protein Cd Antigen Cd182 protein Cxcr2 protein Cmkar2 protein Gpcr16 protein Il8rb protein

Information sourced from Uniprot.org