CMT Positive Control peptide (STJ504304)
SPECIFICATIONS
General Information
| Short Description | CMT Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ICMT |
| Gene ID | 23463 |
| Uniprot ID | ICMT_HUMAN |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
| Peptide Name | Protein-S-Isoprenylcysteine O-MethyltransferaseIsoprenylcysteine CarboxylmethyltransferasePrenylated Protein Carboxyl MethyltransferasePpmtPrenylcysteine Carboxyl MethyltransferasePccmt |
| Database Links | Reactome: R-HSA-163841Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Protein-S-Isoprenylcysteine O-Methyltransferase proteinIsoprenylcysteine Carboxylmethyltransferase proteinPrenylated Protein Carboxyl Methyltransferase proteinPpmt proteinPrenylcysteine Carboxyl Methyltransferase proteinPccmt proteinICMT proteinPCCMT protein |
Information sourced from Uniprot.org