Chimaerin beta 3 Blocking Peptide peptide (STJ503847)

SKU:
STJ503847-250

Shipping:
Free Shipping
Current Stock:
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Chimaerin beta 3 Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: CHN2
Gene ID: 1124
Uniprot ID: CHIO_HUMAN
Immunogen Region: 1-100
Immunogen: Synthetic peptide taken within amino acid region 1-100 on human beta-chimaerin isoform 3 protein.
Tissue Specificity Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Function GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Peptide Name Beta-Chimaerin
Beta-Chimerin
Rho Gtpase-Activating Protein 3
Database Links Reactome: R-HSA-9013149
Cellular Localisation Membrane
Peripheral Membrane Protein
Alternative Peptide Names Beta-Chimaerin protein
Beta-Chimerin protein
Rho Gtpase-Activating Protein 3 protein
CHN2 protein
ARHGAP3 protein
BCH protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance