CD68 Positive Control for STJ500480 peptide (STJ505606)
SPECIFICATIONS
ImmunogenPurified Protein
General Information
| Short Description | CD68 Positive Control for STJ500480 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:2, 500-1:5, 000 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Cd68 |
| Gene ID | 12514 |
| Uniprot ID | CD68_MOUSE |
| Immunogen | Purified Protein |
| Specificity | This is positive control is recommended for use in combination with CD68 antibody STJ500480. |
Additional Info
| Tissue Specificity | Expressed in tissue macrophages and to a lesser extent in dendritic cells. |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Peptide Name | MacrosialinCd Antigen Cd68 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | Isoform Long: Endosome MembraneSingle-Pass Type I Membrane ProteinLysosome MembraneIsoform Short: Cell Membrane |
| Alternative Peptide Names | Macrosialin proteinCd Antigen Cd68 proteinCd68 protein |
Information sourced from Uniprot.org