| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
CD39 Positive Control for STJ500889 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:2, 500-1:5, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ENTPD1 |
| Gene ID: |
953 |
| Uniprot ID: |
ENTP1_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with CD39 antibody STJ500889. |
| Immunogen: |
EctoNucleoside TriPhosphate Diphosphohydrolase 1 purified protein. |
| Tissue Specificity | Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only. |
| Post Translational Modifications | The N-terminus is blocked. Palmitoylated in the N-terminal part. |
| Function | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |
| Peptide Name | Ectonucleoside Triphosphate Diphosphohydrolase 1Ntpdase 1Ecto-Atp Diphosphohydrolase 1Ecto-Atpdase 1Ecto-Atpase 1Ecto-ApyraseLymphoid Cell Activation AntigenCd Antigen Cd39 |
| Database Links | Reactome: R-HSA-8850843Reactome: R-HSA-9660826 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Ectonucleoside Triphosphate Diphosphohydrolase 1 proteinNtpdase 1 proteinEcto-Atp Diphosphohydrolase 1 proteinEcto-Atpdase 1 proteinEcto-Atpase 1 proteinEcto-Apyrase proteinLymphoid Cell Activation Antigen proteinCd Antigen Cd39 proteinENTPD1 proteinCD39 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
