CD39 Blocking Peptide for STJ500891 peptide (STJ505711)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 380-430 on mouse EctoNucleoside TriPhosphate Diphosphohydrolase 1 protein.
General Information
| Short Description | CD39 Blocking Peptide for STJ500891 is synthetically produced from the 380-430 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Entpd1 |
| Gene ID | 12495 |
| Uniprot ID | ENTP1_MOUSE |
| Immunogen | Synthetic peptide taken within amino acid region 380-430 on mouse EctoNucleoside TriPhosphate Diphosphohydrolase 1 protein. |
| Immunogen Region | 380-430 |
| Specificity | This blocking peptide is recommended for use in combination with CD39 antibody, STJ500891 |
Additional Info
| Post Translational Modifications | N-glycosylated. The N-terminus is blocked. Palmitoylated on Cys-13.which is required for caveola targeting. |
| Function | Catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides. By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. |
| Peptide Name | Ectonucleoside Triphosphate Diphosphohydrolase 1Ntpdase 1Atp DiphosphohydrolaseAtp-DphAtpdaseEcto-Atp Diphosphohydrolase 1Ecto-Atpdase 1Ecto-Atpase 1Ecto-ApyraseLymphoid Cell Activation AntigenNucleoside Triphosphate Diphosphohydrolase 1Ntpdase1Cd Antigen Cd39 |
| Database Links | Reactome: R-MMU-8850843 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCaveola |
| Alternative Peptide Names | Ectonucleoside Triphosphate Diphosphohydrolase 1 proteinNtpdase 1 proteinAtp Diphosphohydrolase proteinAtp-Dph proteinAtpdase proteinEcto-Atp Diphosphohydrolase 1 proteinEcto-Atpdase 1 proteinEcto-Atpase 1 proteinEcto-Apyrase proteinLymphoid Cell Activation Antigen proteinNucleoside Triphosphate Diphosphohydrolase 1 proteinNtpdase1 proteinCd Antigen Cd39 proteinEntpd1 proteinCd39 protein |
Information sourced from Uniprot.org