CCR3 Blocking Peptide peptide (STJ503783)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1-50 on human CCR3 protein.
General Information
| Short Description | CCR3 Blocking Peptide is synthetically produced from the 1-50 aa sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | CCR3 |
| Gene ID | 1232 |
| Uniprot ID | CCR3_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein. |
| Immunogen Region | 1-50 aa |
Additional Info
| Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
| Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
| Peptide Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | C-C Chemokine Receptor Type 3 proteinC C Ckr3 proteinC-C Ckr-3 proteinCc-Ckr-3 proteinCcr-3 proteinCcr3 proteinCkr 3 proteinCkr3 proteinEosinophil Eotaxin Receptor proteinCd Antigen Cd193 proteinCCR3 proteinCMKBR3 protein |
Information sourced from Uniprot.org