| Tissue Specificity | Expressed by cells of hematopoietic origin. Expressed in skin in suprabasal layers and hair follicles, in brain by neurons and glial cells and by osteoblasts, osteocytes, osteoclasts (at protein level). |
| Function | Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. |
| Peptide Name | Cannabinoid Receptor 2Cb-2Cb2Mcb2 |
| Database Links | Reactome: R-MMU-373076Reactome: -MMU-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonLocalizes To Apical Dendrite Of Pyramidal Neurons |
| Alternative Peptide Names | Cannabinoid Receptor 2 proteinCb-2 proteinCb2 proteinMcb2 proteinCnr2 protein |
Information sourced from Uniprot.org