C1orf146 Blocking Peptide for STJ500314 peptide (STJ503756)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 100-180 on human C1orf146 protein.
General Information
| Short Description | C1orf146 Blocking Peptide for STJ500314 is synthetically produced from the 100-180 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SPO16 |
| Gene ID | 388649 |
| Uniprot ID | SPO16_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 100-180 on human C1orf146 protein. |
| Immunogen Region | 100-180 |
| Specificity | This blocking peptide is recommended for use in combination with C1orf146 antibody, STJ500314 |
Additional Info
| Function | Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC) thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates. |
| Peptide Name | Protein Spo16 HomologSynaptonemal Complex Reinforcing Element |
| Cellular Localisation | Chromosome |
| Alternative Peptide Names | Protein Spo16 Homolog proteinSynaptonemal Complex Reinforcing Element proteinSPO16 proteinC1orf146 proteinSCRE protein |
Information sourced from Uniprot.org