C15orf42 Positive Control peptide (STJ505237)
SPECIFICATIONS
General Information
| Short Description | C15orf42 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | TICRR |
| Gene ID | 90381 |
| Uniprot ID | TICRR_HUMAN |
Additional Info
| Function | Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation. |
| Peptide Name | TreslinTopbp1-Interacting Checkpoint And Replication RegulatorTopbp1-Interacting - Replication-Stimulating Protein |
| Cellular Localisation | NucleusAssociates With Chromatin |
| Alternative Peptide Names | Treslin proteinTopbp1-Interacting Checkpoint And Replication Regulator proteinTopbp1-Interacting - Replication-Stimulating Protein proteinTICRR proteinC15orf42 protein |
Information sourced from Uniprot.org