Posted by M.Popov on 12th Nov 2020
Trial size HIF1A antibodies available in the Antibody Validation Project
Trial size HIF1A antibodies available in the Antibody Validation Project
Introduction:
HIF1A, also known as hypoxia inducible factor 1 subunit alpha, is the master regulator of cellular and systemic response to hypoxia and activates the transcription of over 40 different genes, which serve highly important functions of sustaining life and maintaining normal homeostasis. HIF1A is widely used in the pharmacological industry for many different conditions and we provide a number of trial sized antibodies, which are suitable for HIF1A research purposes, and to help you make the right decision and find the best suited antibody for you, please find the answers to some of the key topics regarding HIF1A that we have provided in the links below.
- What is HIF1A?
- Where is HIF1A found?
- What role does HIF1A play in disease?
- HIF1A antibodies in the Antibody Validation project
- Customer reviewed HIF1A antibodies
- Other HIF1A antibodies available in the Antibody Validation Project
- Popular HIF1A antibodies not currently in the Antibody Validation Project
- How does the Antibody Validation Project work?
What is HIF1A?
Hypoxia inducible factor 1 subunit alpha (HIF1A) regulates parts of the adenosine pathway. Particularly, HIF1A regulates the expression of the ADORA2B receptor, by binding to the HRE of CD73(its promoter), allowing adenosine transport across the cell membrane.
Where is HIF1A found?
HIF1A is found throughout the body, mostly in bone marrow, the gall bladder and appendix. The lowest concentration of HIF1A is in the pancreas and the salivary gland.
What role does HIF1A play in disease?
Functioning as a master transcriptional regulator of systemic and cellular response, HIF1A activates the transcription of many genes, whose proteins are taking part in oxygen delivery, energy metabolism and angiogenesis. HIF1A is often overexpressed in many human cancers, prompting tumor growth and metastasis growth via initiation of angiogenesis and regulation of cellular metabolism to battle hypoxia.
HIF1A antibodies in the Antibody Validation project
St John's Laboratory offers a variety of trial size primary antibodies which target HIF1A, which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.
Customer reviewed HIF1A antibodies
Model | Name | Host | Clonality | Rating | Application Tested |
---|---|---|---|---|---|
STJ93498 | Anti-HIF-1α antibody | Rabbit | Polyclonal | 4 | WB |
Other HIF1A antibodies available in the Antibody Validation Project
Model | Name | Host | Clonality | Recommended Applications |
---|---|---|---|---|
STJ140040 | Anti-HIF1a antibody | Goat | Polyclonal | WB |
STJ140124 | Anti-HIF1a antibody | Goat | Polyclonal | WB |
STJ150026 | Mouse HIF1A ELISA Kit | ELISA | ||
STJ150065 | Rat HIF1A ELISA Kit | ELISA | ||
STJ150138 | Human HIF1A ELISA Kit | ELISA | ||
STJ93498 | Anti-HIF- alpha antibody | Rabbit | Polyclonal | ELISA,IHC,WB |
STJ97168 | Anti-HIF- alpha antibody | Rabbit | Polyclonal | WB |
STJ98135 | Anti-HIF- alpha antibody | Mouse | Monoclonal | WB,IHC,IF,ELISA |
Popular HIF1A antibodies not currently in the Antibody Validation Project
Model | Name | Host | Clonality | Recommended Applications |
---|---|---|---|---|
STJ113863 | Anti-HIF1A Antibody | Rabbit | Polyclonal | WB |
STJ119210 | Anti-HIF1A Antibody | Rabbit | Polyclonal | WB,IHC,IF |
STJ28187 | Anti-HIF1A Antibody | Rabbit | Polyclonal | WB |
STJ29997 | Anti-HIF1A Antibody | Rabbit | Polyclonal | WB |
STJ501334 | Anti-HIF-1-Alpha isoform 1 Antibody | Rabbit | Polyclonal | ELISA,IP,WB |
STJ501335 | Anti-HIF-1-Alpha isoform 1 + 2 Antibody | Rabbit | Polyclonal | ELISA,IP,WB |
STJ501336 | Anti-HIF-1-Alpha isoform 1 Antibody BIOTIN | Rabbit | Polyclonal | ELISA,IP,WB |
STJ501337 | Anti-HIF-1-Alpha isoform 1 Antibody FITC | Rabbit | Polyclonal | ELISA,IP,WB |
STJ501338 | Anti-HIF-1-Alpha isoform 1 + 2 Antibody BIOTIN | Rabbit | Polyclonal | ELISA,IP,WB |
STJ501339 | Anti-HIF-1-Alpha isoform 1 + 2 Antibody FITC | Rabbit | Polyclonal | ELISA,IP,WB |
How does the Antibody Validation Project work?
In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.
The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.
Find out more here.