Biotinylated Mouse CD62P/SELP protein (C-Avi-His) {Biotin} (STJP012827)
SPECIFICATIONS
HostMammalian Cells
ConjugationBiotin
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Biotinylated Mouse CD62P/SELP-C-Avi-His protein was developed from mammalian cells and has a target region of C-Avi-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8Β°C for one week. Store at-20 to-80Β°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/Β΅g as determined by LAL test. |
Target Information
| Gene Symbol | Selp |
| Gene ID | 20344 |
| Uniprot ID | LYAM3_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Trp42ΒAla709 |
Additional Info
| Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3). |
| Protein Name | P-SelectinCd62 Antigen-Like Family Member PGranule Membrane Protein 140Gmp-140Leukocyte-Endothelial Cell Adhesion Molecule 3Lecam3Platelet Activation Dependent Granule-External Membrane ProteinPadgemCd Antigen Cd62p |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | P-Selectin proteinCd62 Antigen-Like Family Member P proteinGranule Membrane Protein 140 proteinGmp-140 proteinLeukocyte-Endothelial Cell Adhesion Molecule 3 proteinLecam3 proteinPlatelet Activation Dependent Granule-External Membrane Protein proteinPadgem proteinCd Antigen Cd62p proteinSelp proteinGrmp protein |
Information sourced from Uniprot.org