Biotinylated Human IL5 protein (C-His-Avi) {Biotin} (STJP012415)

Name: Biotinylated Human IL5 protein (C-His-Avi) {Biotin} (STJP012415)
SKU: STJP012415-100
Price: 834.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationBiotin

ImmunogenHomo sapiens (Human)

STJP012415-100

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Short Description	Biotinylated Human IL5-C-His-Avi protein was developed from mammalian cells and has a target region of C-His-Avi. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Biotin
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Protein Name	Interleukin-5 Il-5 B-Cell Differentiation Factor I Eosinophil Differentiation Factor T-Cell Replacing Factor Trf
Database Links	Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-912526
Cellular Localisation	Secreted
Alternative Protein Names	Interleukin-5 protein Il-5 protein B-Cell Differentiation Factor I protein Eosinophil Differentiation Factor protein T-Cell Replacing Factor protein Trf protein IL5 protein

Information sourced from Uniprot.org