Aquaporin 3 Blocking Peptide peptide (STJ503663)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein.
General Information
| Short Description | Aquaporin 3 Blocking Peptide is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Aqp3 |
| Gene ID | 65133 |
| Uniprot ID | AQP3_RAT |
| Immunogen | Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein. |
| Immunogen Region | 200-250 |
Additional Info
| Tissue Specificity | Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon. |
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance. |
| Peptide Name | Aquaporin-3Aqp-331.4 Kda Water Channel ProteinAquaglyceroporin-3 |
| Database Links | Reactome: R-RNO-432040Reactome: -RNO-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell Membrane |
| Alternative Peptide Names | Aquaporin-3 proteinAqp-3 protein31.4 Kda Water Channel Protein proteinAquaglyceroporin-3 proteinAqp3 protein |
Information sourced from Uniprot.org