Anti-ZYX antibody [R01-8C8] (STJA0035015)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Zyxin
General Information
| Short Description | Rabbit monoclonal anti-ZYX for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-8C8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ZYX |
| Gene ID | 7791 |
| Uniprot ID | ZYX_HUMAN |
| Immunogen | A synthetic peptide of human Zyxin |
Additional Info
| Function | Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression. |
| Protein Name | ZyxinZyxin-2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCell JunctionFocal AdhesionAssociates With The Actin Cytoskeleton Near The Adhesion PlaquesEnters The Nucleus In The Presence Of Hesx1 |
| Alternative Antibody Names | Anti-Zyxin antibodyAnti-Zyxin-2 antibodyAnti-ZYX antibody |
Information sourced from Uniprot.org