Anti-ZYX antibody (350-572) (STJ26156)

Name: Anti-ZYX antibody (350-572) (STJ26156)
SKU: STJ26156
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ26156

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Short Description	Rabbit polyclonal ZYX (350-572) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ZYX
Gene ID	7791
Uniprot ID	ZYX_HUMAN
Immunogen Region	350-572
Immunogen Sequence	PLTLKEVEELEQLTQQLMQD MEHPQRQNVAVNELCGRCHQ PLARAQPAVRALGQLFHIAC FTCHQCAQQLQGQQFYSLEG APYCEGCYTDTLEKCNTCGE PITDRMLRATGKAYHPHCFT CVVCARPLEGTSFIVDQANR PHCVPDYHKQYAPRCSVCSE PIMPEPGRDETVRVVALDKN FHMKCYKCEDCGKPLSIEAD DNGCFPLDGHVLCRKCHTAR AQT
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 350-572 of human Zyxinin (NP_003452.1).

Function	Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
Protein Name	Zyxin Zyxin-2
Database Links
Cellular Localisation	Cytoplasm Cytoskeleton Nucleus Cell Junction Focal Adhesion Associates With The Actin Cytoskeleton Near The Adhesion Plaques Enters The Nucleus In The Presence Of Hesx1
Alternative Antibody Names	Anti-Zyxin antibody Anti-Zyxin-2 antibody Anti-ZYX antibody

Information sourced from Uniprot.org