Anti-ZNF638 antibody (1271-1320) (STJ94542)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human ZNF638. AA range:1271-1320
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 638 (1271-1320) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF638 |
| Gene ID | 27332 |
| Uniprot ID | ZN638_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZNF638. AA range:1271-1320 |
| Immunogen Region | 1271-1320 |
| Specificity | NP220 Polyclonal Antibody detects endogenous levels of NP220 protein. |
Additional Info
| Function | Transcription factor that binds to cytidine clusters in double-stranded DNA. Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed. Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4. Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. May also regulate alternative splicing of target genes during adipogenesis. |
| Protein Name | Zinc Finger Protein 638Cutaneous T-Cell Lymphoma-Associated Antigen Se33-1Ctcl-Associated Antigen Se33-1Nuclear Protein 220Zinc Finger Matrin-Like Protein |
| Database Links | Reactome: R-HSA-381340 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Zinc Finger Protein 638 antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Se33-1 antibodyAnti-Ctcl-Associated Antigen Se33-1 antibodyAnti-Nuclear Protein 220 antibodyAnti-Zinc Finger Matrin-Like Protein antibodyAnti-ZNF638 antibodyAnti-NP220 antibodyAnti-ZFML antibody |
Information sourced from Uniprot.org