Anti-ZNF423 antibody [N328B/37R] (STJA0019039)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
General Information
| Short Description | Mouse monoclonal Zinc Finger Protein 423 antibody for use in ICC, IHC and WB in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/IHC/WB |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N328B/37R |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1.13 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | Znf423 |
| Gene ID | 94187 |
| Uniprot ID | ZN423_MOUSE |
Additional Info
| Function | Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation.this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. |
| Protein Name | Zinc Finger Protein 423Early B-Cell Factor-Associated Zinc Finger ProteinOlf1/Ebf-Associated Zinc Finger ProteinSmad- And Olf-Interacting Zinc Finger Protein |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 423 antibodyAnti-Early B-Cell Factor-Associated Zinc Finger Protein antibodyAnti-Olf1/Ebf-Associated Zinc Finger Protein antibodyAnti-Smad- And Olf-Interacting Zinc Finger Protein antibodyAnti-Znf423 antibodyAnti-Ebfaz antibodyAnti-Kiaa0760 antibodyAnti-Nur12 antibodyAnti-Oaz antibodyAnti-Zfp423 antibody |
Information sourced from Uniprot.org