| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc finger protein 423 (848-898 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZNF423 |
| Gene ID: |
23090 |
| Uniprot ID: |
ZN423_HUMAN |
| Immunogen Region: |
848-898 aa |
| Specificity: |
This antibody detects endogenous levels of ZN423 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human ZN423 at the amino acid range 848-898 |
| Function | Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation.this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. |
| Protein Name | Zinc Finger Protein 423Olf1/Ebf-Associated Zinc Finger ProteinHoazSmad- And Olf-Interacting Zinc Finger Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 423 antibodyAnti-Olf1/Ebf-Associated Zinc Finger Protein antibodyAnti-Hoaz antibodyAnti-Smad- And Olf-Interacting Zinc Finger Protein antibodyAnti-ZNF423 antibodyAnti-KIAA0760 antibodyAnti-NPHP14 antibodyAnti-OAZ antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
