Anti-ZDHHC4 antibody (110-210) (STJ119958)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ZDHHC4 (110-210) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZDHHC4 |
| Gene ID | 55146 |
| Uniprot ID | ZDHC4_HUMAN |
| Immunogen Region | 110-210 |
| Immunogen Sequence | VNLFFFTLTCGTNPGIITKA NELLFLHVYEFDEVMFPKNV RCSTCDLRKPARSKHCSVCN WCVHRFDHHCVWVNNCIGAW NIRYFLIYVLTLTASAATVA I |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 110-210 of human ZDHHC4 (NP_060576.1). |
Additional Info
| Function | Palmitoyltransferase that catalyzes the addition of palmitate onto protein substrates including the D(2) dopamine receptor DRD2, GSK3B or MAVS. Mediates GSK3B palmitoylation to prevent its AKT1-mediated phosphorylation leading to activation of the STAT3 signaling pathway. Also catalyzes MAVS palmitoylation which promotes its stabilization and activation by inhibiting 'Lys-48'- but facilitating 'Lys-63'-linked ubiquitination. |
| Protein Name | Palmitoyltransferase Zdhhc4Zinc Finger Dhhc Domain-Containing Protein 4Dhhc-4Zinc Finger Protein 374 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCell Membrane |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc4 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 4 antibodyAnti-Dhhc-4 antibodyAnti-Zinc Finger Protein 374 antibodyAnti-ZDHHC4 antibodyAnti-ZNF374 antibodyAnti-DC1 antibodyAnti-UNQ5787 antibodyAnti-PRO19576 antibody |
Information sourced from Uniprot.org