| Short Description : | Rabbit polyclonal ZDHHC4 (110-210) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZDHHC4 |
| Gene ID: | 55146 |
| Uniprot ID: | ZDHC4_HUMAN |
| Immunogen Region: | 110-210 |
| Immunogen Sequence: | VNLFFFTLTCGTNPGIITKA NELLFLHVYEFDEVMFPKNV RCSTCDLRKPARSKHCSVCN WCVHRFDHHCVWVNNCIGAW NIRYFLIYVLTLTASAATVA I |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 110-210 of human ZDHHC4 (NP_060576.1). |
| Function | Palmitoyltransferase that catalyzes the addition of palmitate onto protein substrates including the D(2) dopamine receptor DRD2, GSK3B or MAVS. Mediates GSK3B palmitoylation to prevent its AKT1-mediated phosphorylation leading to activation of the STAT3 signaling pathway. Also catalyzes MAVS palmitoylation which promotes its stabilization and activation by inhibiting 'Lys-48'- but facilitating 'Lys-63'-linked ubiquitination. |
| Protein Name | Palmitoyltransferase Zdhhc4Zinc Finger Dhhc Domain-Containing Protein 4Dhhc-4Zinc Finger Protein 374 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCell Membrane |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc4 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 4 antibodyAnti-Dhhc-4 antibodyAnti-Zinc Finger Protein 374 antibodyAnti-ZDHHC4 antibodyAnti-ZNF374 antibodyAnti-DC1 antibodyAnti-UNQ5787 antibodyAnti-PRO19576 antibody |
Information sourced from Uniprot.org
