| Function | Endoplasmic reticulum-localized palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes. Has a palmitoyltransferase activity toward NCDN and regulates NCDN association with endosome membranes through this palmitoylation. May play a role in cell proliferation. Also has a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response. Functions as an adapter that recruits IRF3 to STING1 to promote the activation of that key transcriptional regulator of type I interferon (IFN)-dependent immune response. |
| Protein Name | Palmitoyltransferase Zdhhc11Zinc Finger Dhhc Domain-Containing Protein 11Dhhc-11Zinc Finger Protein 399 |
| Database Links | Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc11 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 11 antibodyAnti-Dhhc-11 antibodyAnti-Zinc Finger Protein 399 antibodyAnti-ZDHHC11 antibodyAnti-ZNF399 antibody |
Information sourced from Uniprot.org
