Anti-ZC3HC1 antibody (320-369) (STJ94494)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NIPA. AA range:320-369
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger C3HC-type protein 1 (320-369) for use in WB, IF and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZC3HC1 |
| Gene ID | 51530 |
| Uniprot ID | ZC3C1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NIPA. AA range:320-369 |
| Immunogen Region | 320-369 |
| Specificity | NIPA Polyclonal Antibody detects endogenous levels of NIPA protein. |
Additional Info
| Tissue Specificity | Widely expressed. Highly expressed in heart, skeletal muscle and testis. Expressed in brain, placenta, lung, kidney, liver, pancreas, spleen, thymus, prostate, ovary small intestine and colon. Weakly or not expressed in leukocytes. |
| Post Translational Modifications | Phosphorylated. May also be weakly phosphorylated on Tyr residues. |
| Function | Required for proper positioning of a substantial amount of TPR at the nuclear basket (NB) through interaction with TPR. |
| Protein Name | Zinc Finger C3hc-Type Protein 1Nuclear-Interacting Partner Of AlkHnipaNuclear-Interacting Partner Of Anaplastic Lymphoma Kinase |
| Database Links | Reactome: R-HSA-9725371 |
| Cellular Localisation | NucleusNucleus EnvelopeResident Of The Nuclear Basket (Nb)Occurs At The Nuclear Envelopes (Ne) Of All Tpr-Containing Cell TypesIncluding Proliferating And Non-DividingTerminally Differentiated Cells Of Different Morphogenetic Origin |
| Alternative Antibody Names | Anti-Zinc Finger C3hc-Type Protein 1 antibodyAnti-Nuclear-Interacting Partner Of Alk antibodyAnti-Hnipa antibodyAnti-Nuclear-Interacting Partner Of Anaplastic Lymphoma Kinase antibodyAnti-ZC3HC1 antibodyAnti-NIPA antibodyAnti-HSPC216 antibody |
Information sourced from Uniprot.org