| Tissue Specificity | Isoform 1: Expressed in fetal and adult brain. Expressed in fetal and adult temporal lobe. Isoform 6: Expressed in fetal and adult brain. Expressed in fetal and adult temporal lobe. |
| Function | RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Required for spermatogenesis via involvement in circRNA biogenesis. Regulates the pre-mRNA processing of ATP5MC1.preventing its degradation. Also binds the poly(A) tail of mRNAs.controlling poly(A) length in neuronal cells. |
| Protein Name | Zinc Finger Ccch Domain-Containing Protein 14Mammalian Suppressor Of Tau Pathology-2Msut-2Renal Carcinoma Antigen Ny-Ren-37 |
| Database Links | |
| Cellular Localisation | Nucleus SpeckleColocalizes With Poly(A) Rna In Nuclear SpecklesIsoform 1: Nucleus SpeckleIsoform 3: Nucleus SpeckleIsoform 6: Cytoplasm |
| Alternative Antibody Names | Anti-Zinc Finger Ccch Domain-Containing Protein 14 antibodyAnti-Mammalian Suppressor Of Tau Pathology-2 antibodyAnti-Msut-2 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-37 antibodyAnti-ZC3H14 antibody |
Information sourced from Uniprot.org
