Anti-PKD1L2 antibody (1-306) (STJ117153)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PKD1L2 (1-306) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PKD1L2 |
| Gene ID | 114780 |
| Uniprot ID | PK1L2_HUMAN |
| Immunogen Region | 1-306 |
| Immunogen Sequence | MGEDSPVAMFSWYLDNTPTE QAEPLLDACRLRGFWPRSLT LLQSNTSTLLLNSSFLQSRG EVIRIRATALTRHAYGEDTY VISTVPPREVPACTIAPEEG TVLTSFAIFCNASTALGPLE FCFCLESGSCLHCGPEPALP SVYLPLGEENNDFVLTVVIS ATNRAGDTQQTQAMAKVALG DTCVEDVAFQAAVSEKIPTA LQGEGGPEQLLQLAKAVSSM LNQEHESQGSGQSLSIDVR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of human PKD1L2 (NP_001265352.1). |
Additional Info
| Tissue Specificity | Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. |
| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. |
| Function | May function as a G-protein-coupled receptor. |
| Protein Name | Polycystin-1-Like Protein 2Polycystin-1l2Pc1-Like 2 ProteinPolycystic Kidney Disease Protein 1-Like 2 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Polycystin-1-Like Protein 2 antibodyAnti-Polycystin-1l2 antibodyAnti-Pc1-Like 2 Protein antibodyAnti-Polycystic Kidney Disease Protein 1-Like 2 antibodyAnti-PKD1L2 antibodyAnti-KIAA1879 antibodyAnti-PC1L2 antibody |
Information sourced from Uniprot.org