Anti-ZBTB1 antibody (STJA0008018)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ZBTB1
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger and BTB domain-containing protein 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZBTB1 |
| Gene ID | 22890 |
| Uniprot ID | ZBTB1_HUMAN |
| Immunogen | Synthesized peptide derived from human ZBTB1 |
| Specificity | This antibody detects endogenous levels of ZBTB1 at Human, Mouse |
Additional Info
| Function | Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusNucleoplasmLocalized In Dot-Like Structures In The NucleusColocalized With Smrt In Nuclear BodiesThe Sumoylated Form Is Preferentially Located In The Nucleoplasm Outside The Nuclear Bodies |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 1 antibodyAnti-ZBTB1 antibodyAnti-KIAA0997 antibody |
Information sourced from Uniprot.org