Anti-YRDC antibody (214-264 aa) (STJ198010)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human YRDC at the amino acid range 214-264
General Information
| Short Description | Rabbit polyclonal anti-Threonylcarbamoyl-AMP synthase (214-264 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | YRDC |
| Gene ID | 79693 |
| Uniprot ID | YRDC_HUMAN |
| Immunogen | Synthesized peptide derived from the human YRDC at the amino acid range 214-264 |
| Immunogen Region | 214-264 aa |
| Specificity | This antibody detects endogenous levels of human YRDC |
Additional Info
| Function | Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters. |
| Protein Name | Threonylcarbamoyl-Amp SynthaseDopamine Receptor-Interacting Protein 3Ischemia/Reperfusion-Inducible Protein HomologHirip |
| Database Links | |
| Cellular Localisation | CytoplasmMitochondrionCell MembranePeripheral Membrane ProteinA Large Fraction Localizes In The CytoplasmWhereas A Smaller Fraction Is Imported To Mitochondria |
| Alternative Antibody Names | Anti-Threonylcarbamoyl-Amp Synthase antibodyAnti-Dopamine Receptor-Interacting Protein 3 antibodyAnti-Ischemia/Reperfusion-Inducible Protein Homolog antibodyAnti-Hirip antibodyAnti-YRDC antibodyAnti-DRIP3 antibodyAnti-IRIP antibody |
Information sourced from Uniprot.org