• Western blot analysis of various lysates using YPEL5 Rabbit polyclonal antibody (STJ116543) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-YPEL5 antibody (1-121) (STJ116543)

SKU:
STJ116543

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-YPEL5 (1-121) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: YPEL5
Gene ID: 51646
Uniprot ID: YPEL5_HUMAN
Immunogen Region: 1-121
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1).
Immunogen Sequence: MGRIFLDHIGGTRLFSCANC DTILTNRSELISTRFTGATG RAFLFNKVVNLQYSEVQDRV MLTGRHMVRDVSCKNCNSKL GWIYEFATEDSQRYKEGRVI LERALVRESEGFEEHVPSDN S
Function Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation.
Protein Name Protein Yippee-Like 5
Database Links Reactome: R-HSA-6798695
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle Pole
Midbody
Deteted In Nucleus And At The Centrosome During Interphase
During Mitosis
Detected On The Mitotic Spindle
At Spindle Poles And At The Midbody
Alternative Antibody Names Anti-Protein Yippee-Like 5 antibody
Anti-YPEL5 antibody
Anti-CGI-127 antibody

Information sourced from Uniprot.org

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