Anti-YPEL5 antibody (1-121) (STJ116543)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal YPEL5 (1-121) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | YPEL5 |
| Gene ID | 51646 |
| Uniprot ID | YPEL5_HUMAN |
| Immunogen Region | 1-121 |
| Immunogen Sequence | MGRIFLDHIGGTRLFSCANC DTILTNRSELISTRFTGATG RAFLFNKVVNLQYSEVQDRV MLTGRHMVRDVSCKNCNSKL GWIYEFATEDSQRYKEGRVI LERALVRESEGFEEHVPSDN S |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1). |
Additional Info
| Function | Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation. |
| Protein Name | Protein Yippee-Like 5 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleMidbodyDeteted In Nucleus And At The Centrosome During InterphaseDuring MitosisDetected On The Mitotic SpindleAt Spindle Poles And At The Midbody |
| Alternative Antibody Names | Anti-Protein Yippee-Like 5 antibodyAnti-YPEL5 antibodyAnti-CGI-127 antibody |
Information sourced from Uniprot.org