Anti-XYLT1 antibody (312-362 aa) (STJ193713)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human XYLT1 at the amino acid range 312-362
General Information
| Short Description | Rabbit polyclonal anti-Xylosyltransferase 1 (312-362 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | XYLT1 |
| Gene ID | 64131 |
| Uniprot ID | XYLT1_HUMAN |
| Immunogen | Synthesized peptide derived from the human XYLT1 at the amino acid range 312-362 |
| Immunogen Region | 312-362 aa |
| Specificity | This antibody detects endogenous levels of XYLT1 at Human/Mouse/Rat |
Additional Info
| Post Translational Modifications | Contains 7 disulfide bonds. N-glycosylated. |
| Function | Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification. |
| Protein Name | Xylosyltransferase 1Peptide O-Xylosyltransferase 1Xylosyltransferase IXt-IXylt-I |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedDetected Predominantly In The Golgi Apparatus |
| Alternative Antibody Names | Anti-Xylosyltransferase 1 antibodyAnti-Peptide O-Xylosyltransferase 1 antibodyAnti-Xylosyltransferase I antibodyAnti-Xt-I antibodyAnti-Xylt-I antibodyAnti-XYLT1 antibodyAnti-XT1 antibody |
Information sourced from Uniprot.org