![Anti-XRCC5/6-Ku-holo; p70/86 antibody [EBS-C-003] (STJ16101072)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149788/302539/STJ16101072_1__59701.1646940694.jpg?c=1 "Anti-XRCC5/6-Ku-holo; p70/86 antibody [EBS-C-003] (STJ16101072)")
![Anti-XRCC5/6-Ku-holo; p70/86 antibody [EBS-C-003] (STJ16101072)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149788/302539/STJ16101072_1__59701.1646940694.jpg?c=1 "Anti-XRCC5/6-Ku-holo; p70/86 antibody [EBS-C-003] (STJ16101072)")
Anti-XRCC5/6-Ku-holo; p70/86 antibody [EBS-C-003] (STJ16101072)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with HeLa cells. Fusion partner: SP2/0.
General Information
| Short Description | Mouse monoclonal antibody anti-XRCC5/6-Ku-holo; p70/86 is suitable for use in Immunofluorescence and Immunohistochemistry research applications. |
| Applications | IF/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EBS-C-003 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | Immunofluorescence (0.5-1, 0 ยตg/ml). Immunohistology (1-2 ยตg/ml for 30-60 minutes at RT). |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Immunogen | A BALB/c mouse was immunized with HeLa cells. Fusion partner: SP2/0. |
Additional Info
| Background | EBS-C-003 recognizes Ku protein or XRCC5/6 (X-ray repair cross complementing protein 5/6) , involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. It serves as autoantigen in patients with rheumatic diseases. |
Information sourced from Uniprot.org