| Host: |
Mouse |
| Applications: |
IF/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-XRCC5/6-Ku-holo; p70/86 is suitable for use in Immunofluorescence and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
EBS-C-003 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
PBS with 0.02% Sodium Azide. |
| Purification: |
Affinity purified from tissue culture. |
| Concentration: |
Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: |
Immunofluorescence (0.5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 minutes at RT). |
| Storage Instruction: |
Store for up to 1 year at 2-8°C upon receipt. |
| Immunogen: |
A BALB/c mouse was immunized with HeLa cells. Fusion partner: SP2/0. |
| Background | EBS-C-003 recognizes Ku protein or XRCC5/6 (X-ray repair cross complementing protein 5/6) , involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. It serves as autoantigen in patients with rheumatic diseases. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
