• Western blot analysis of extracts of various cell lines, using XPNPEP2 antibody (STJ112293) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-XPNPEP2 antibody (22-240) (STJ112293)

SKU:
STJ112293

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-XPNPEP2 (22-240) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: XPNPEP2
Gene ID: 7512
Uniprot ID: XPP2_HUMAN
Immunogen Region: 22-240
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4).
Immunogen Sequence: HTKPVDLGGQDVRNCSTNPP YLPVTVVNTTMSLTALRQQM QTQNLSAYIIPGTDAHMNEY IGQHDERRAWITGFTGSAGT AVVTMKKAAVWTDSRYWTQA ERQMDCNWELHKEVGTTPIV TWLLTEIPAGGRVGFDPFLL SIDTWESYDLALQGSNRQLV SITTNLVDLVWGSERPPVPN QPIYALQEAFTGSTWQEKVS GVRSQMQKHQKVPTAVLLS
Tissue Specificity Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary.
Post Translational Modifications N-glycosylated.
Function Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Protein Name Xaa-Pro Aminopeptidase 2
Aminoacylproline Aminopeptidase
Membrane-Bound Aminopeptidase P
Membrane-Bound App
Membrane-Bound Amp
Mamp
X-Pro Aminopeptidase 2
Database Links Reactome: R-HSA-163125
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Antibody Names Anti-Xaa-Pro Aminopeptidase 2 antibody
Anti-Aminoacylproline Aminopeptidase antibody
Anti-Membrane-Bound Aminopeptidase P antibody
Anti-Membrane-Bound App antibody
Anti-Membrane-Bound Amp antibody
Anti-Mamp antibody
Anti-X-Pro Aminopeptidase 2 antibody
Anti-XPNPEP2 antibody

Information sourced from Uniprot.org

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