Anti-XCL1/XCL2 antibody (Internal) (STJ71844)

SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
STJ71844-100
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General Information

Short DescriptionGoat polyclonal antibody anti-XCL1/XCL2 (Internal) is suitable for use in ELISA research applications.
ApplicationsPep-ELISA
HostGoat
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration0.5 mg/mL
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution RangePeptide ELISA: antibody detection limit dilution 1:16000.
WB: Preliminary experiments gave an approx 80kDa band in Human Peripheral Blood Mononucleocytes lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an expla
Formulation0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage InstructionStore at-20°C on receipt and minimise freeze-thaw cycles.

Target Information

Gene SymbolXCL1
Gene ID6375
Uniprot IDXCL1_HUMAN
Accession NumberNP_002986.1; NP_003166.1
Immunogen RegionInternal
Immunogen SequenceRDVVRSMDRKSNTRN
SpecificityXCL1 and CXL2 are almost identical and therefore this antibody is expected to recognize both proteins.

Additional Info

Function Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Protein Name Lymphotactin
Atac
C Motif Chemokine 1
Cytokine Scm-1
Lymphotaxin
Scm-1-Alpha
Small-Inducible Cytokine C1
Xc Chemokine Ligand 1
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-416476
Cellular Localisation Secreted
Alternative Antibody Names Anti-Lymphotactin antibody
Anti-Atac antibody
Anti-C Motif Chemokine 1 antibody
Anti-Cytokine Scm-1 antibody
Anti-Lymphotaxin antibody
Anti-Scm-1-Alpha antibody
Anti-Small-Inducible Cytokine C1 antibody
Anti-Xc Chemokine Ligand 1 antibody
Anti-XCL1 antibody
Anti-LTN antibody
Anti-SCYC1 antibody

Information sourced from Uniprot.org

Citations

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