Anti-WNT5B antibody (300-359 aa) [R03-7C4] (STJA0015591)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Wnt5b
General Information
| Short Description | Rabbit monoclonal anti-Wnt5b (300-359 aa) for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R03-7C4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000FC 1:50-1:100 |
| Formulation | Liquid in PBS pH7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | WNT5B |
| Gene ID | 81029 |
| Uniprot ID | WNT5B_HUMAN |
| Immunogen | A synthesized peptide derived from human Wnt5b |
| Immunogen Region | 300-359 aa |
Additional Info
| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. |
| Protein Name | Protein Wnt-5b |
| Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-4086400 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-5b antibodyAnti-WNT5B antibody |
Information sourced from Uniprot.org