Anti-WNT5B antibody (300-359 aa) [R03-7C4] (STJA0015591)

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STJA0015591-100
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Short Description :Rabbit monoclonal anti-Wnt5b (300-359 aa) for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R03-7C4
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
FC 1:50-1:100
Formulation:Liquid in PBS pH7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:WNT5B
Gene ID:81029
Uniprot ID:WNT5B_HUMAN
Immunogen:A synthesized peptide derived from human Wnt5b
Immunogen Region:300-359 aa
Post Translational Modifications Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Protein Name Protein Wnt-5b
Database Links Reactome: R-HSA-3238698
Reactome: R-HSA-4086400
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Protein Wnt-5b antibody
Anti-WNT5B antibody

Information sourced from Uniprot.org