Anti-WNT10B antibody [5A7] (STJ98452)

Name: Anti-WNT10B antibody [5A7] (STJ98452)
SKU: STJ98452
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenPurified recombinant fragment of human Wnt-10b expressed in E. Coli.

STJ98452

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Short Description	Mouse monoclonal anti-Protein Wnt-10b for use in WB, IHC, IF and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/ELISA
Host	Mouse
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	5A7
Isotype	IgG1
Conjugation	Unconjugated
Purification	Affinity purification
Dilution Range	WB 1:500-1:2000 IHC 1:200-1:1000 IF 1:200-1:1000 ELISA 1:10000
Formulation	Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT10B
Gene ID	7480
Uniprot ID	WN10B_HUMAN
Immunogen	Purified recombinant fragment of human Wnt-10b expressed in E. Coli.
Specificity	Wnt-10b Monoclonal Antibody detects endogenous levels of Wnt-10b protein.

Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin.
Protein Name	Protein Wnt-10b Protein Wnt-12
Database Links	Reactome: R-HSA-3238698 Reactome: R-HSA-373080 Reactome: R-HSA-381340
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Protein Wnt-10b antibody Anti-Protein Wnt-12 antibody Anti-WNT10B antibody Anti-WNT12 antibody

Information sourced from Uniprot.org