| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-WAS/WASL-interacting protein family member 1 (421-470 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
WIPF1 |
| Gene ID: |
7456 |
| Uniprot ID: |
WIPF1_HUMAN |
| Immunogen Region: |
421-470 aa |
| Specificity: |
WIP Polyclonal Antibody detects endogenous levels of WIP protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human WIPF1 at the amino acid range 421-470 |
| Function | Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles. Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus. |
| Protein Name | Was/Wasl-Interacting Protein Family Member 1Protein Prpl-2Wiskott-Aldrich Syndrome Protein-Interacting ProteinWasp-Interacting Protein |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-5663213Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9664422 |
| Cellular Localisation | Cytoplasmic VesicleCytoplasmCytoskeletonCell ProjectionRuffleVesicle Surfaces And Along Actin TailsColocalizes With Actin Stress FibersWhen Coexpressed With WaslNo Longer Associated With Actin Filaments But Accumulated In Perinuclear And Cortical Areas Like Wasl |
| Alternative Antibody Names | Anti-Was/Wasl-Interacting Protein Family Member 1 antibodyAnti-Protein Prpl-2 antibodyAnti-Wiskott-Aldrich Syndrome Protein-Interacting Protein antibodyAnti-Wasp-Interacting Protein antibodyAnti-WIPF1 antibodyAnti-WASPIP antibodyAnti-WIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
