Anti-WDR68 antibody [R26-1E-6] (STJA0035565)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human DCAF7
General Information
| Short Description | Rabbit monoclonal anti-WDR68 for use in WB, IHC-P and FC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/FC |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R26-1E-6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100-1:200FC 1:50 |
| Formulation | Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DCAF7 |
| Gene ID | 10238 |
| Uniprot ID | DCAF7_HUMAN |
| Immunogen | A synthesized peptide derived from human DCAF7 |
Additional Info
| Function | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
| Protein Name | Ddb1- And Cul4-Associated Factor 7Wd Repeat-Containing Protein 68Wd Repeat-Containing Protein An11 Homolog |
| Database Links | Reactome: R-HSA-390471Reactome: R-HSA-8951664 |
| Cellular Localisation | CytoplasmNucleusOverexpression Of Diahp1 Or Active Rhoa Causes Translocation From The Nucleus To Cytoplasm |
| Alternative Antibody Names | Anti-Ddb1- And Cul4-Associated Factor 7 antibodyAnti-Wd Repeat-Containing Protein 68 antibodyAnti-Wd Repeat-Containing Protein An11 Homolog antibodyAnti-DCAF7 antibodyAnti-HAN11 antibodyAnti-WDR68 antibody |
Information sourced from Uniprot.org