| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-WDFY4 (1-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
WDFY4 |
| Gene ID: |
57705 |
| Uniprot ID: |
WDFY4_HUMAN |
| Immunogen Region: |
1-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human WDFY4 (NP_065996.1). |
| Immunogen Sequence: |
MEAEDLSKAEDRNEDPGSKN EGQLAAVQPDVPHGGQSSSP TALWDMLERKFLEYQQLTHK SPIERQKSLLSLLPLFLKAW EHSVGIICFPSLQRLAEDVS DQLAQQLQKALVGKPAEQAR LAAGQLLWWKGDVDQDGYLL LKSVYVLTGTDSETLGRVAE |
| Function | Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Also plays a role in B-cell survival through regulation of autophagy. |
| Protein Name | Wd Repeat- And Fyve Domain-Containing Protein 4 |
| Cellular Localisation | Early EndosomeEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Wd Repeat- And Fyve Domain-Containing Protein 4 antibodyAnti-WDFY4 antibodyAnti-C10orf64 antibodyAnti-KIAA1607 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
